Biosynthesis of glycosides

Steviol glycosides are found in large concentrations within the leaves for the Paraguayan perennial herb Stevia rebaudiana and their intense sweetness, in addition to large focus in Stevia leaf muscle, has made all of them the subject of analysis interest for more than 100 years. Steviol glycosides are diterpenoids whose biosynthetic paths share four tips in common with gibberellic acid formation. The convergence of genomics and plant biochemistry has actually led to the quick elucidation of this genes coding the different enzymes when you look at the biosynthetic pathway. Functional characterization of this enzymes coded for by those genetics is on-going. The first committed part of the path could be the synthesis regarding the aglycone steviol and also the various glycosides based in the leaf structure derive from the elaboration of steviol by several glucosyltransferases.

Graphical abstract

Steviol glycosides are observed in large levels in the leaves of the Paraguayan perennial herb Stevia rebaudiana, their intense sweetness and high concentration in Stevia leaf structure makes all of them the subject of research interest for more than a century. The convergence of genomics and plant biochemistry has generated the rapid elucidation for the genetics coding for the numerous enzymes in biosynthetic pathway.

Keywords

• Stevia rebaudiana;
• Asteraceae;
• Stevia;
• Biosynthesis;
• Diterpene glycoside;
• Terpene cyclase;
• P450;
• Glucosyltransferase